Endocrine Abstracts

İntroduction: Gitelman syndrome is characterized with hypokalemia, hypomagnesemia, hypocalciuria, metabolic alkalosis and neurological symptoms like muscle weakness. The association of GS and type 1 diabetes is rare, only described in a few case reports. We report a patient with unusual combination of Gitelman syndrome, Type 1 Diabetes Mellitus whose presentation was erytrocytosis.Case: A 26-year old male was diagnosed as Gitelman’s syndrome 5...

Introduction: Thyroid dysfunctions and autoimmunity may concur in the pathogenesis of hemostasis abnormalities. Hashimoto’s thyroiditis (HT) is a frequently chronic autoimmune disease in thyroid gland. The aim of our study were to comparison the hemostatic parameters in patients with HT and control subjects.Method: A total of 52 women were evaluated. Age, TSH, free T3, free T4, anti M, anti Tg, TAFI, TFPI, PAI-1, tPA, PF-4, fib...

A 44-year-old man with 6 months history of headache, fatique, depressive mood, anorexia, impotence, decreased libido, poliuria and polidypsia. The results of the physical examination were normal, except the patient had noduler guatr. Baseline hormonal investigations and dinamic tests showed panhypopituitarism and partial central diabetes insipidus. Magnetic resonance imaging (MRI) of the pituitary gland showed enlarged pituitary gland and a marked thickening (4.5 mm) of the in...

Aim: In our study, in regard with the women cases of obesity, we have aimed at determining the correlation that existed among the anemia markers, insulin resistance (IR) and fact of Metabolic syndrome (MetS).Method: We have conducted our assessment 67 women who had resorted to our clinic due to their obesity complaints and were in the premenopausal and mean age 36.7±8.8 years. We have put forward the demographic data and measured the biochemical (fa...

Aim: Hypoadiponectinemia is known to be associated with insulin resistance, diabetes and obesity. Since gestational diabetes is together with increased body mass index (BMI) and decreased insulin sensitivity, the evaluation of adiponectin levels in these patients is interesting. We investigated the relationship between adiponectin and glucose tolerance during pregnancy and after delivery.Materials and methods: We evaluated plasma adiponectin levels, insu...

Although adrenal gland involvement may be seen in patients with diffuse (non-Hodgkin) lymphoma, primary adrenal lymphoma is quite rare and adrenal insufficiency accompanies the clinical picture in 2/3 of cases.Case: A 70-year-old male patient presenting with anorexia and weight loss was referred to our clinic for bilateral adrenal masses, which were detected by abdominal computerized tomography (CT) as 5.2×5.2×2.7 cm in the right adrenal and 11...

A 49-year-old man with history of nodular goitre operation was referred to our clinic because of MTC in postoperative pathology. He had hypertension, postoperative hypothyroidism, no family history of thyroid carcinoma and sudden death. Laboratuary investigations showed high level of calcitonin (C) (763 pg/ml; normal<150), Carcino embryogenic antigen (CEA) (175 ng/ml; normal<2.5), normal thyroid function tests, parathormone, urinary catecholamines. Ser904 polymorphism ...

Aim: Comparison of the parameters of obesity with the newly-defined adipocytokines in females applying to our clinic for obesity.Method: Demographical data of 36 obese females were determined. Cases were classified as obese and morbid obese according to BMI values. Biochemical parameters were measured for all the cases. Thicknesses of subcutaneous and visceral fatty tissues were measured on ultrasonography. Statistical significances were evaluated by app...

Aims: Impact of gestational diabetes mellitus on the coagulation system, dynamics involved at a pathophysiological level and the exact mechanism remain unclear.To evaluate association between diabetes-related parameters and haemostatic factors in order to search for a tendency of thrombosis in gestational diabetes mellitus.Methods and Material: Nineteen pregnant women who had gestational diabetes mellitus, 16 healthy pregnant and 1...

Aim: Diabetic rethinopathy is an important microvascular complication in diabetic patients. The association between hyperlipidemia and diabetic rethinopathy remains elusive. Lipoprotein associated phospholipase A2 (Lp-PLA2) is Ca independent serine kinase that hydrolyses oxidized LDL and forms lysilphoshotidylcholine and free fatty acid. The aim of the study was to determine serum levels of Lp-PLA2, traditional lipids, apolipoproteins in patients with diabetic rethinopathy and...